Lead Generation

Hit to Lead campaign through de-novo design, core hopping, ligand
growing with focus on off-target selectivity and freedom to operate.

slide 1
slide 1
slide 1
Image Slide 2
Image Slide 2
Image Slide 2
Image Slide 1
Image Slide 3
  • Optimization of on-target potency
  • Fragment hybridization for ligand growing
  • Design for off-target selectivity
  • Protein-ligand interaction fingerprints
  • Lead quality assessment with ML DMPK global filters
  • Identifying structural alerts for potential toxicity
  • Screening of leads on our molecular similarity engine
  • Druglikeness assessment

To Know More