Chemical Biology
Design of appropriate experiments leveraging the molecular
structure to address issues with different targets and key assets
Protein-protein interfaces analysis - Protein construct design for crystallography and assays
- Protein-protein docking and effect of mutations
- Design of PROTACs for protein degradation
- Mode of action hypotheses for leads
- Investigation of causes for drug resistance
- Assessing covalent inhibition potential of targets
- Design of chemical biology experiments based on molecular structure
- Identification of allosteric pockets